A novel role for microglia in minimizing excitotoxicity

A Functional Role for Microglia in Epilepsy

Microglia are the immune competent cells of the CNS and comprise the major mechanism of self-defense against brain injury, infections and disease. Activation of microglia occur as a response to these insults, and both neurotoxic and neuroprotective factors can be released (Streit et al., 1999, Streit, 2002, Schwartz, 2003, Schwartz et al., 2006). There is a great deal of evidence suggesting tha...

passivity in waiting for godot and endgame: a psychoanalytic reading

this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...

A Novel Market Optimization Model in order to Minimizing Environmental Cost Caused by Plants

Nowadays generation capacity in traditional grid depends on fossil fuels and contributes significantly to the increase of pollution emission. In deregulated grids in addition to using demand response programs (DRPs) to reducing the cost of electricity production, peak clipping and improve reliability use of green Plants such as hydro plant, wind plant become widespread. In a smart grid, end use...

A novel role for Sema3A in neuroprotection from injury mediated by activated microglia.

Microglia exist under physiological conditions in a resting state but become activated after neuronal injury. Recent studies have highlighted the reciprocal role of neurons in controlling both the number and activity of microglia. In this study, microglia derived from newborn rat cortices were cultured and activated by interferon-gamma (IFNgamma) treatment, then exposed to recombinant Sema3A or...

Microglia: a novel treatment target in gliomas.